我們身體的各部份均是由細胞組成，眼睛晶片也自當然不例外。759Please respect copyright.ＰＥＮＡＮＡJVqYSfw7QV
但細胞裡頭有著各式各樣的細胞器官，例如負責製造能源的粒線體(mitochondria)、收藏DNA的細胞核(nucleus)等，它們顯然並不是透明的。759Please respect copyright.ＰＥＮＡＮＡo25cdMnZpd
759Please respect copyright.ＰＥＮＡＮＡjvIem2mMcC
究竟身體有甚麼方法可以製造透明且能讓光線通過的眼鏡晶片呢?759Please respect copyright.ＰＥＮＡＮＡekHMOQ0BmP
759Please respect copyright.ＰＥＮＡＮＡjrPFCUO5WV
759Please respect copyright.ＰＥＮＡＮＡUPrSb0dSfC
759Please respect copyright.ＰＥＮＡＮＡiwYteOJusC
(圖2)答案很簡單，就是把那些細胞器官通通摧毀。759Please respect copyright.ＰＥＮＡＮＡOLMADyVBjY
759Please respect copyright.ＰＥＮＡＮＡCwrLAo8K9y
759Please respect copyright.ＰＥＮＡＮＡtm7GntWGOj
從圖中可見，晶片的外圍有著表皮細胞(Epithelial cells)以及纖維細胞(Fibre cells)，唯獨是中間區域的細胞，它們的細胞器官均接近得消失得一乾二淨。759Please respect copyright.ＰＥＮＡＮＡoWd7oKWd5n
759Please respect copyright.ＰＥＮＡＮＡu9H6KRPzXQ
759Please respect copyright.ＰＥＮＡＮＡoG2yGrFR3p
(圖3)有科學家利用班馬魚作動物模型，並將兩款細胞器官分別染成綠色及紅色。759Please respect copyright.ＰＥＮＡＮＡS15l50xjNq
759Please respect copyright.ＰＥＮＡＮＡ1ywzcLj9rS
759Please respect copyright.ＰＥＮＡＮＡdnO1hhTf4j
從圖中可見，直至班馬魚受精後約59小時左右，綠色及紅色均分別清晰可見及有著其獨特的分佈，表示兩款細胞器官非常健在。759Please respect copyright.ＰＥＮＡＮＡUdTiUUiTga
但在約60小時打後，紅色和綠色開始有著衰退的現象，亦即表示細胞器官開始逐漸被受摧毀。759Please respect copyright.ＰＥＮＡＮＡi20h8weJ1r
759Please respect copyright.ＰＥＮＡＮＡCh5MFLRvnR
759Please respect copyright.ＰＥＮＡＮＡY1BBN5FzwP
(圖4)找出眼睛晶片的細胞器官被受摧毀的時段後，研究人員便著手進行一系列的實驗，759Please respect copyright.ＰＥＮＡＮＡbV4rT1o9bt
並發現名為plaat的蛋白質負責在細胞器官的外膜進行破壞，因而引發細胞器官摧毀的過程。759Please respect copyright.ＰＥＮＡＮＡKGq1xutGOo
759Please respect copyright.ＰＥＮＡＮＡoNHkCEJBk7
759Please respect copyright.ＰＥＮＡＮＡB3U1qMbV3k
圖中為班馬魚的眼睛晶片，可見因為缺乏plaat蛋白質的緣故，細胞器官沒能完整摧毀，其晶片亦變得相對上混濁及不透光，影像亦較為不清晰。759Please respect copyright.ＰＥＮＡＮＡnr4kFwUnlp
759Please respect copyright.ＰＥＮＡＮＡ528IptZ7w6
759Please respect copyright.ＰＥＮＡＮＡ0zUGhTmc12
(圖5)除班馬魚外，研究人員亦有利用老鼠進行實驗。759Please respect copyright.ＰＥＮＡＮＡk36fi2CddY
759Please respect copyright.ＰＥＮＡＮＡo0RGg1ycJ1
759Please respect copyright.ＰＥＮＡＮＡAAYh430DjX
跟班馬魚一樣，缺乏plaat蛋白質的老鼠眼睛晶片變得混濁及不透光，並影響視線。759Please respect copyright.ＰＥＮＡＮＡfGA3IFhLhh
759Please respect copyright.ＰＥＮＡＮＡXDJ0nRBNrK
759Please respect copyright.ＰＥＮＡＮＡUe9c1IAFIu
759Please respect copyright.ＰＥＮＡＮＡ1X37bjcrOa
759Please respect copyright.ＰＥＮＡＮＡlWm4T1tNci
759Please respect copyright.ＰＥＮＡＮＡ7QWZeSoD8w
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。759Please respect copyright.ＰＥＮＡＮＡXsWQpKpT16
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc759Please respect copyright.ＰＥＮＡＮＡwguruOImZK
759Please respect copyright.ＰＥＮＡＮＡJVHdgX378w
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。759Please respect copyright.ＰＥＮＡＮＡomRm30PXyS
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Link:759Please respect copyright.ＰＥＮＡＮＡYNVMP0MBjk
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio759Please respect copyright.ＰＥＮＡＮＡJWVHYzRbz9
759Please respect copyright.ＰＥＮＡＮＡwEqUwTrn4Z
759Please respect copyright.ＰＥＮＡＮＡ9jvu0XX5en
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。759Please respect copyright.ＰＥＮＡＮＡa6ZaGxgENI
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Ref1:https://www.nature.com/articles/s41586-021-03439-w759Please respect copyright.ＰＥＮＡＮＡhbikSDlk6k
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