世界非常殘酷，美味可口的食物很多時候都是高脂高卡路里。917Please respect copyright.ＰＥＮＡＮＡuRGKKJ39bb
917Please respect copyright.ＰＥＮＡＮＡ3lsPz7DiQG
917Please respect copyright.ＰＥＮＡＮＡfJaoPDQfa1
如果餐單的卡路里長期是以脂肪為主導的話，又是否會更容易產生癌症呢?917Please respect copyright.ＰＥＮＡＮＡQmbvtBo3tI
917Please respect copyright.ＰＥＮＡＮＡDZTmFgCxgW
（圖2）有科學家對此進行研究（Ref1)，餵食老鼠為期7日脂肪佔總卡路里約60%的餐單，然後再透過血管移植人類的口腔癌細胞，其後密切跟進腫瘤的狀況。917Please respect copyright.ＰＥＮＡＮＡ37g27msSQ4
917Please respect copyright.ＰＥＮＡＮＡy3OACSPmbC
917Please respect copyright.ＰＥＮＡＮＡEs4EsmLtWI
如何跟進? 就是用上集所介紹的螢光技術。917Please respect copyright.ＰＥＮＡＮＡ8sIhiZeBJK
917Please respect copyright.ＰＥＮＡＮＡ8ngGNDrGfl
詳情可見：三十秒科學–透視癌細胞917Please respect copyright.ＰＥＮＡＮＡdzk8egD5V4
- 分享自 LIHKG 討論區917Please respect copyright.ＰＥＮＡＮＡZOyMEi5y66
https://lih.kg/2408323917Please respect copyright.ＰＥＮＡＮＡttYM0ZShPj
917Please respect copyright.ＰＥＮＡＮＡy5bFcSUdDm
917Please respect copyright.ＰＥＮＡＮＡGWxbPrO2Vj
（圖3）從圖中可以看得見，進食脂肪主導餐單的老鼠，原生腫瘤的體積不但更為巨大，而且亦有更高機率出現癌細胞轉移的情況。917Please respect copyright.ＰＥＮＡＮＡw3BqkxNIKE
917Please respect copyright.ＰＥＮＡＮＡwWQ72DcPLL
917Please respect copyright.ＰＥＮＡＮＡmfgumB0bJF
CD36是輔助細胞吸取脂肪酸的蛋白質，當癌細胞的CD36被除去的時候，莫論餐單是否由脂肪主導，原生腫瘤的體積均沒有顯著大變化，而且亦沒有出現癌細胞轉移的情況。917Please respect copyright.ＰＥＮＡＮＡIAsSTXGcHO
917Please respect copyright.ＰＥＮＡＮＡFkT5rHzIZf
（圖4）當細胞遇上棕櫚酸約兩日後，細胞的CD36蛋白質數量亦會因而上升 。917Please respect copyright.ＰＥＮＡＮＡhzVYTYBC3v
917Please respect copyright.ＰＥＮＡＮＡtyMayP9qH6
917Please respect copyright.ＰＥＮＡＮＡYR0YoOZuJy
從右圖中可以清晰見得到，經過棕櫚酸「調教」過的癌細胞，移植到老鼠後會出現非常明顯的癌細胞轉移過程。917Please respect copyright.ＰＥＮＡＮＡZwi2RvxKBJ
而當癌細胞的CD36蛋白質被移除後，癌細胞轉移過程亦再沒有發生。917Please respect copyright.ＰＥＮＡＮＡNzywIpMQdn
917Please respect copyright.ＰＥＮＡＮＡpU355oQ67J
現時有不少藥物嘗試針對CD36來醫治癌細胞或阻止其進行轉移的程序，但不少藥物均在第二期臨床研究裡頭因為出現副作用或效率未如預期被迫中斷。917Please respect copyright.ＰＥＮＡＮＡtuKFevLbFE
917Please respect copyright.ＰＥＮＡＮＡ16sJPsxbVG
或許需要更多研究理解CD36在細胞的作用或機制，才能設計出輕微副作用的治癌藥物。917Please respect copyright.ＰＥＮＡＮＡY38D2lbtLO
917Please respect copyright.ＰＥＮＡＮＡhjPvt7GML9
917Please respect copyright.ＰＥＮＡＮＡ8I7Pj2cVGZ
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。917Please respect copyright.ＰＥＮＡＮＡacDhQNvqDZ
917Please respect copyright.ＰＥＮＡＮＡXTSUSdDxZd
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc917Please respect copyright.ＰＥＮＡＮＡKDl3rXai5I
917Please respect copyright.ＰＥＮＡＮＡs9PNuJmQZN
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。917Please respect copyright.ＰＥＮＡＮＡUCCcT2oGVl
917Please respect copyright.ＰＥＮＡＮＡQBIUM6yAoU
Link:917Please respect copyright.ＰＥＮＡＮＡhWJ9zkTJ9F
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio917Please respect copyright.ＰＥＮＡＮＡNlJ4eNZVkZ
917Please respect copyright.ＰＥＮＡＮＡAHVg3zxiMB
917Please respect copyright.ＰＥＮＡＮＡg3P3VfehLq
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。917Please respect copyright.ＰＥＮＡＮＡdfI1ljDege
917Please respect copyright.ＰＥＮＡＮＡ5wIDPD2c0W
Ref1:https://pubmed.ncbi.nlm.nih.gov/27974793/917Please respect copyright.ＰＥＮＡＮＡtgWa6sUg0Y
Penana
search
登入arrow_drop_down
註冊arrow_drop_down
