x
肛門塞藥較會常用在兒童或不清醒的病人身上。基於大腸的表面面積非常大，而且鄰近血液循環系統，所以肝門塞藥大多時候均會比口服藥物更有效率進入血液裡頭。897Please respect copyright.ＰＥＮＡＮＡbWasv1o5Tz
897Please respect copyright.ＰＥＮＡＮＡnIyWPzfRqH
897Please respect copyright.ＰＥＮＡＮＡxtvM8x2ZEv
只不過最終是以口服還是肛門塞藥服用，請遵照醫生的吩咐及指示。897Please respect copyright.ＰＥＮＡＮＡSFi6diBhti
897Please respect copyright.ＰＥＮＡＮＡwmmdfviDh1
897Please respect copyright.ＰＥＮＡＮＡjfow1mHRzM
（圖2）有科學家受腸道鉤蟲啟發，設計出勾狀式藥物，並發表文章匯報成果（Ref1)。897Please respect copyright.ＰＥＮＡＮＡRN6662oj5n
勾狀式藥物附上蠟質塗層，遇上體溫後便會溶化，並引致金屬制的勾爪抓緊腸道組織。897Please respect copyright.ＰＥＮＡＮＡfkaDm3xIfQ
897Please respect copyright.ＰＥＮＡＮＡkXMBqCIrnf
897Please respect copyright.ＰＥＮＡＮＡFj5H0QnkOu
897Please respect copyright.ＰＥＮＡＮＡVVTqzfi8QG
（圖3）利用儀器以高壓方式將勾狀式藥物送進腸道位置後，藥物便會從插著腸道內的金屬爪管道排出，進入血液循環系統裡頭。897Please respect copyright.ＰＥＮＡＮＡQRC3qc1ULw
897Please respect copyright.ＰＥＮＡＮＡxG4QKPZrTR
897Please respect copyright.ＰＥＮＡＮＡQxvJis3OvN
897Please respect copyright.ＰＥＮＡＮＡLRbLv2JpKx
（圖4）如圖中所見，紅線為勾狀式裝置包裝藥物肛塞進入老鼠腸道，而黑線為直接將藥物肛塞進入老鼠腸道的結果。897Please respect copyright.ＰＥＮＡＮＡySCODy2qsA
897Please respect copyright.ＰＥＮＡＮＡvympnAfzZ9
897Please respect copyright.ＰＥＮＡＮＡtNOEACQYGa
利用勾狀式裝置包裝的方式送藥，藥物停留在血液的時間明顯有所增長!897Please respect copyright.ＰＥＮＡＮＡOojwzmJRW9
897Please respect copyright.ＰＥＮＡＮＡTTrhif50wz
而經過計算後，意欲往70kg成人輸送10mg Ketorolac的話，大概需要4900個1.5mm長的勾狀藥物。897Please respect copyright.ＰＥＮＡＮＡTX09HCos05
897Please respect copyright.ＰＥＮＡＮＡhoKMbOl2V5
文中的所有研究結果均透過老鼠身上所得，能否套用在人類身上使用為未知之數。897Please respect copyright.ＰＥＮＡＮＡFQJpbf1OwA
897Please respect copyright.ＰＥＮＡＮＡBb950WAS1f
另一關於腸道送藥的研究，可參閱:https://www.penana.com/article/475900897Please respect copyright.ＰＥＮＡＮＡ231C4txNHI
897Please respect copyright.ＰＥＮＡＮＡeyJdHh2IKO
897Please respect copyright.ＰＥＮＡＮＡgzMr9c6l2t
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。897Please respect copyright.ＰＥＮＡＮＡIfmiV1J2AR
897Please respect copyright.ＰＥＮＡＮＡha3k36dHsf
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc897Please respect copyright.ＰＥＮＡＮＡusoNIuUqzO
897Please respect copyright.ＰＥＮＡＮＡjxBBCx6w1c
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。897Please respect copyright.ＰＥＮＡＮＡXPsmrKk22i
897Please respect copyright.ＰＥＮＡＮＡ8czNGeniaw
Link:897Please respect copyright.ＰＥＮＡＮＡLDG6NasjYA
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio897Please respect copyright.ＰＥＮＡＮＡcxXtxTeAL8
897Please respect copyright.ＰＥＮＡＮＡR1MRrge7e7
897Please respect copyright.ＰＥＮＡＮＡR9shugeIjP
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。897Please respect copyright.ＰＥＮＡＮＡUHVomtQDr5
897Please respect copyright.ＰＥＮＡＮＡk5FbYwHjGJ
https://www.instagram.com/potatopigtongue/897Please respect copyright.ＰＥＮＡＮＡvS9vjtg5es
897Please respect copyright.ＰＥＮＡＮＡMlIiSvuRdT
897Please respect copyright.ＰＥＮＡＮＡZsYIY0iMdT
897Please respect copyright.ＰＥＮＡＮＡOXRYzTUTSA
Ref1:https://advances.sciencemag.org/content/6/44/eabb4133897Please respect copyright.ＰＥＮＡＮＡvc46AN4xN4
