我們身體的各部份均是由細胞組成，眼睛晶片也自當然不例外。758Please respect copyright.ＰＥＮＡＮＡcTi4ZEXsDo
但細胞裡頭有著各式各樣的細胞器官，例如負責製造能源的粒線體(mitochondria)、收藏DNA的細胞核(nucleus)等，它們顯然並不是透明的。758Please respect copyright.ＰＥＮＡＮＡ1sPEXbYnxv
758Please respect copyright.ＰＥＮＡＮＡGbSG2sXC8J
究竟身體有甚麼方法可以製造透明且能讓光線通過的眼鏡晶片呢?758Please respect copyright.ＰＥＮＡＮＡuURqyNcjEk
758Please respect copyright.ＰＥＮＡＮＡdxfl3dCFoY
758Please respect copyright.ＰＥＮＡＮＡxnW32oUg0s
758Please respect copyright.ＰＥＮＡＮＡAKAd5Ufbvz
(圖2)答案很簡單，就是把那些細胞器官通通摧毀。758Please respect copyright.ＰＥＮＡＮＡzxYUc6hy50
758Please respect copyright.ＰＥＮＡＮＡcbGsOZcSgk
758Please respect copyright.ＰＥＮＡＮＡ0Ztj0rHSVl
從圖中可見，晶片的外圍有著表皮細胞(Epithelial cells)以及纖維細胞(Fibre cells)，唯獨是中間區域的細胞，它們的細胞器官均接近得消失得一乾二淨。758Please respect copyright.ＰＥＮＡＮＡv15qDu9GbL
758Please respect copyright.ＰＥＮＡＮＡXBBuqjHq1x
758Please respect copyright.ＰＥＮＡＮＡY0RP6moaJT
(圖3)有科學家利用班馬魚作動物模型，並將兩款細胞器官分別染成綠色及紅色。758Please respect copyright.ＰＥＮＡＮＡ0wdycWmDK6
758Please respect copyright.ＰＥＮＡＮＡESH6Xf82ma
758Please respect copyright.ＰＥＮＡＮＡWkKEJf3zPi
從圖中可見，直至班馬魚受精後約59小時左右，綠色及紅色均分別清晰可見及有著其獨特的分佈，表示兩款細胞器官非常健在。758Please respect copyright.ＰＥＮＡＮＡF3ETYpXHPd
但在約60小時打後，紅色和綠色開始有著衰退的現象，亦即表示細胞器官開始逐漸被受摧毀。758Please respect copyright.ＰＥＮＡＮＡfFZ4Gv8p9u
758Please respect copyright.ＰＥＮＡＮＡ1Ki3IgNLMf
758Please respect copyright.ＰＥＮＡＮＡ8QZMHVsF7T
(圖4)找出眼睛晶片的細胞器官被受摧毀的時段後，研究人員便著手進行一系列的實驗，758Please respect copyright.ＰＥＮＡＮＡ50LXxK2clN
並發現名為plaat的蛋白質負責在細胞器官的外膜進行破壞，因而引發細胞器官摧毀的過程。758Please respect copyright.ＰＥＮＡＮＡxZP0T6gxCI
758Please respect copyright.ＰＥＮＡＮＡt0ZNr9t617
758Please respect copyright.ＰＥＮＡＮＡDB8nUHJeoJ
圖中為班馬魚的眼睛晶片，可見因為缺乏plaat蛋白質的緣故，細胞器官沒能完整摧毀，其晶片亦變得相對上混濁及不透光，影像亦較為不清晰。758Please respect copyright.ＰＥＮＡＮＡcVlAMAD0Dv
758Please respect copyright.ＰＥＮＡＮＡs7Q3ux10Z0
758Please respect copyright.ＰＥＮＡＮＡ7SH6UnBPbX
(圖5)除班馬魚外，研究人員亦有利用老鼠進行實驗。758Please respect copyright.ＰＥＮＡＮＡUYc9gpM0TC
758Please respect copyright.ＰＥＮＡＮＡcWZBaVJYxF
758Please respect copyright.ＰＥＮＡＮＡHOYDhEBqjN
跟班馬魚一樣，缺乏plaat蛋白質的老鼠眼睛晶片變得混濁及不透光，並影響視線。758Please respect copyright.ＰＥＮＡＮＡ5wdI3CFIFu
758Please respect copyright.ＰＥＮＡＮＡv0rCjFxHYP
758Please respect copyright.ＰＥＮＡＮＡzMI2nUGAYh
758Please respect copyright.ＰＥＮＡＮＡTxr0BWmrUM
758Please respect copyright.ＰＥＮＡＮＡZ3480FVMeP
758Please respect copyright.ＰＥＮＡＮＡZJaDZooXfy
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。758Please respect copyright.ＰＥＮＡＮＡgZUy3Bsmmb
758Please respect copyright.ＰＥＮＡＮＡcqzZY2aW0u
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc758Please respect copyright.ＰＥＮＡＮＡPWurDwUEc7
758Please respect copyright.ＰＥＮＡＮＡnvHRQ29Ew3
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。758Please respect copyright.ＰＥＮＡＮＡoN2t4ws6bR
758Please respect copyright.ＰＥＮＡＮＡ8Y8guEY0fC
Link:758Please respect copyright.ＰＥＮＡＮＡXHk0xpPSVe
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio758Please respect copyright.ＰＥＮＡＮＡakQfCSUwMr
758Please respect copyright.ＰＥＮＡＮＡtHfRBFmm7B
758Please respect copyright.ＰＥＮＡＮＡK0sXrnSVdt
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。758Please respect copyright.ＰＥＮＡＮＡpL6D1NTNv5
758Please respect copyright.ＰＥＮＡＮＡoATiMONVim
Ref1:https://www.nature.com/articles/s41586-021-03439-w758Please respect copyright.ＰＥＮＡＮＡS5KGotUDJi
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