世界非常殘酷，美味可口的食物很多時候都是高脂高卡路里。918Please respect copyright.ＰＥＮＡＮＡGVIY5TgTZe
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如果餐單的卡路里長期是以脂肪為主導的話，又是否會更容易產生癌症呢?918Please respect copyright.ＰＥＮＡＮＡPJDQOCgiS6
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（圖2）有科學家對此進行研究（Ref1)，餵食老鼠為期7日脂肪佔總卡路里約60%的餐單，然後再透過血管移植人類的口腔癌細胞，其後密切跟進腫瘤的狀況。918Please respect copyright.ＰＥＮＡＮＡfQWOa0bE6Y
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如何跟進? 就是用上集所介紹的螢光技術。918Please respect copyright.ＰＥＮＡＮＡvR3Pcg4kT4
918Please respect copyright.ＰＥＮＡＮＡe9x1ml2G2v
詳情可見：三十秒科學–透視癌細胞918Please respect copyright.ＰＥＮＡＮＡeFffISKDfi
- 分享自 LIHKG 討論區918Please respect copyright.ＰＥＮＡＮＡcnwkVIKfbh
https://lih.kg/2408323918Please respect copyright.ＰＥＮＡＮＡbpSbz7MBk7
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（圖3）從圖中可以看得見，進食脂肪主導餐單的老鼠，原生腫瘤的體積不但更為巨大，而且亦有更高機率出現癌細胞轉移的情況。918Please respect copyright.ＰＥＮＡＮＡsVeW8GHPQx
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CD36是輔助細胞吸取脂肪酸的蛋白質，當癌細胞的CD36被除去的時候，莫論餐單是否由脂肪主導，原生腫瘤的體積均沒有顯著大變化，而且亦沒有出現癌細胞轉移的情況。918Please respect copyright.ＰＥＮＡＮＡik4VYdGANK
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（圖4）當細胞遇上棕櫚酸約兩日後，細胞的CD36蛋白質數量亦會因而上升 。918Please respect copyright.ＰＥＮＡＮＡ12qt6SLh6Q
918Please respect copyright.ＰＥＮＡＮＡyfNz95rhA3
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從右圖中可以清晰見得到，經過棕櫚酸「調教」過的癌細胞，移植到老鼠後會出現非常明顯的癌細胞轉移過程。918Please respect copyright.ＰＥＮＡＮＡtVia9EnsQg
而當癌細胞的CD36蛋白質被移除後，癌細胞轉移過程亦再沒有發生。918Please respect copyright.ＰＥＮＡＮＡNSkEQQFri9
918Please respect copyright.ＰＥＮＡＮＡy9995oqhT0
現時有不少藥物嘗試針對CD36來醫治癌細胞或阻止其進行轉移的程序，但不少藥物均在第二期臨床研究裡頭因為出現副作用或效率未如預期被迫中斷。918Please respect copyright.ＰＥＮＡＮＡaxjDrfZS3S
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或許需要更多研究理解CD36在細胞的作用或機制，才能設計出輕微副作用的治癌藥物。918Please respect copyright.ＰＥＮＡＮＡtkTdLr9jYd
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。918Please respect copyright.ＰＥＮＡＮＡ87uNKOlF0n
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc918Please respect copyright.ＰＥＮＡＮＡr0LA4QoPj4
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。918Please respect copyright.ＰＥＮＡＮＡcAeGp0FDfk
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Link:918Please respect copyright.ＰＥＮＡＮＡtrRNar0pGs
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio918Please respect copyright.ＰＥＮＡＮＡP0EOyyTAX6
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除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。918Please respect copyright.ＰＥＮＡＮＡKYsS8tYFiV
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Ref1:https://pubmed.ncbi.nlm.nih.gov/27974793/918Please respect copyright.ＰＥＮＡＮＡcyFpDqE3l8
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