A Radiolabeled Fully Human Antibody to Human Aspartyl (Asparaginyl) β-Hydroxylase Is a Promising Agent for Imaging and Therapy of Metastatic Breast Cancer
人天冬氨酰（天冬酰胺酰）β-羥化酶的放射性標記全人抗體是轉移性乳腺癌成像和治療的有前途的藥物305Please respect copyright.ＰＥＮＡＮＡ311jWw9dkb
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PAN-622 偶聯物與 HAAH 和癌細胞的結合。 (A) PAN-622-CHXA" 綴合物通過 ELISA 與重組 HAAH 催化結構域的結合； (B) PAN-622-CHXA" 綴合物與 H460、人肺癌細胞的結合，如通過細胞 ELISA 測量的； (C) PAN-622-DTPA-MAL 綴合物通過 ELISA 與重組 HAAH 催化結構域的結合； (D) PAN-622-DTPA-MAL 15 分鐘和 PAN-622-CHXA” 10:1 結合物與 4T1 小鼠乳腺癌細胞的結合，通過細胞 ELISA 測量。 mAU，毫吸光度單位。 ELISA，酶聯免疫吸附試驗； HAAH，人天冬氨酰（天冬酰胺酰）β-羥化酶。305Please respect copyright.ＰＥＮＡＮＡh19tOD2E1d
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