
Q: A gene string can be represented by an 8-character long string, with choices from 'A', 'C', 'G', and 'T'.
Suppose we need to investigate a mutation from a gene string start to a gene string end where one mutation is defined as one single character changed in the gene string.
- For example, "AACCGGTT" --> "AACCGGTA" is one mutation.
There is also a gene bank bank that records all the valid gene mutations. A gene must be in bank to make it a valid gene string.
Given the two gene strings start and end and the gene bank bank, return the minimum number of mutations needed to mutate from start to end. If there is no such a mutation, return -1.
Note that the starting point is assumed to be valid, so it might not be included in the bank.
A: BFS (Breadth-First Search)260Please respect copyright.PENANA5mRJUGtcLo
// better than use DFS as it just need to find out the shortest path.
class Solution {260Please respect copyright.PENANAW5XHOnQCca
public int minMutation(String start, String end, String[] bank) {260Please respect copyright.PENANAiLE1WKmBgL
// Initialize a queue queue and a set seen. The queue will be used for BFS and the set will be used to prevent visiting a node more than once. Initially, the queue and set should hold start.260Please respect copyright.PENANAeu3Uf9Zbwg
Queue<String> queue = new LinkedList<>();260Please respect copyright.PENANArbHBsYglwt
Set<String> seen = new HashSet<>();260Please respect copyright.PENANAd6wcWBxytb
queue.add(start);260Please respect copyright.PENANAi1dsNzG7QR
seen.add(start);260Please respect copyright.PENANAHpK3QbQem4
260Please respect copyright.PENANAMf4URhAeeF
int steps = 0;260Please respect copyright.PENANAhFMx5pABT1
260Please respect copyright.PENANAhIBMVaygTs
while (!queue.isEmpty()) {260Please respect copyright.PENANAesbYGmDlfW
int nodesInQueue = queue.size();260Please respect copyright.PENANAEK4IusjhNh
for (int j = 0; j < nodesInQueue; j++) {260Please respect copyright.PENANAwkb2kvugkX
String node = queue.remove();260Please respect copyright.PENANADBBUyKeXMX
// Perform a BFS. At each node, if node == end, return the number of steps so far. Otherwise, iterate over all the neighbors. For each neighbor, if neighbor is not in seen and neighbor is in bank, add it to queue and seen.
if (node.equals(end)) {260Please respect copyright.PENANAcQZ1d0iM4C
return steps;260Please respect copyright.PENANAXxBmETrngb
}
for (char c: new char[] {'A', 'C', 'G', 'T'}) {260Please respect copyright.PENANAnYnVExGPft
for (int i = 0; i < node.length(); i++) {260Please respect copyright.PENANA9H8XyJQPcy
String neighbor = node.substring(0, i) + c + node.substring(i + 1);260Please respect copyright.PENANAZ7awXISu4x
if (!seen.contains(neighbor) && Arrays.asList(bank).contains(neighbor)) {260Please respect copyright.PENANALcMywsl24k
queue.add(neighbor);260Please respect copyright.PENANAbttYU0qSUf
seen.add(neighbor);260Please respect copyright.PENANAeJcmWMCkUM
}260Please respect copyright.PENANAdYFb8OHKYn
}260Please respect copyright.PENANAmHGzwPeAcm
}260Please respect copyright.PENANAQRj055EAfu
}260Please respect copyright.PENANAr0dh3TxJit
260Please respect copyright.PENANAcMbT4v8Rtt
steps++;260Please respect copyright.PENANA5gB137hsgw
}260Please respect copyright.PENANAZ3ZHH0nAgu
// If we finish the BFS and did not find end, return -1.260Please respect copyright.PENANALc3vhJnEbO
return -1;260Please respect copyright.PENANA8JpW3pcMhC
}260Please respect copyright.PENANAVKecbpG7iB
}